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FDA Approves Johnson & Johnson's Ketamine-Derived Nasal Spray for Depression
Jan 23, 2025

FDA Approves Johnson & Johnson's Ketamine-Derived Nasal Spray for Depression

The U.S. Food and Drug Administration (FDA) has granted approval for Johnson & Johnson's novel ketamine-derived nasal spray, Spravato, designed to assist millions of Americans coping with severe depression. Fox Business reports that the approval was granted following an FDA priority review, addressing the needs of patients with treatment-resistant depression (TRD).

Spravato is the first monotherapy option for adults with major depressive disorder who have not responded to at least two oral antidepressants. With an estimated 21 million U.S. adults affected by major depressive disorder, Johnson & Johnson notes that approximately one-third do not respond adequately to oral medications alone, significantly impacting their quality of life.

The company revealed that the nasal spray has been administered to over 140,000 patients worldwide and demonstrates depression symptom reduction in as little as 24 hours. The approval highlights a significant advancement in psychiatric care, providing new hope for patients facing limited options with conventional antidepressants.

The contrast in trade figures signifies the U.S.'s role as both a significant importer and exporter in the realm of medicaments. Despite a decline from the previous year's import figures, which were 12.1 billion USD, the diverse range of trade partners underscores the global nature of the pharmaceutical industry. With such dynamics, the approval of new treatments like Spravato plays a crucial role in diversifying available options and meeting the demands of the global market.

Source: IndexBox Market Intelligence Platform

  1. 1. INTRODUCTION

    Making Data-Driven Decisions to Grow Your Business

    1. REPORT DESCRIPTION
    2. RESEARCH METHODOLOGY AND THE AI PLATFORM
    3. DATA-DRIVEN DECISIONS FOR YOUR BUSINESS
    4. GLOSSARY AND SPECIFIC TERMS

  2. 2. EXECUTIVE SUMMARY

    A Quick Overview of Market Performance

    1. KEY FINDINGS
    2. MARKET TRENDS This Chapter is Available Only for the Professional EditionPRO

  3. 3. MARKET OVERVIEW

    Understanding the Current State of The Market and its Prospects

    1. MARKET SIZE: HISTORICAL DATA (2012–2024) AND FORECAST (2025–2035)
    2. CONSUMPTION BY COUNTRY: HISTORICAL DATA (2012–2024) AND FORECAST (2025–2035)
    3. MARKET FORECAST TO 2035

  4. 4. MOST PROMISING PRODUCTS FOR DIVERSIFICATION

    Finding New Products to Diversify Your Business

    1. TOP PRODUCTS TO DIVERSIFY YOUR BUSINESS
    2. BEST-SELLING PRODUCTS
    3. MOST CONSUMED PRODUCTS
    4. MOST TRADED PRODUCTS
    5. MOST PROFITABLE PRODUCTS FOR EXPORT

  5. 5. MOST PROMISING SUPPLYING COUNTRIES

    Choosing the Best Countries to Establish Your Sustainable Supply Chain

    1. TOP COUNTRIES TO SOURCE YOUR PRODUCT
    2. TOP PRODUCING COUNTRIES
    3. TOP EXPORTING COUNTRIES
    4. LOW-COST EXPORTING COUNTRIES

  6. 6. MOST PROMISING OVERSEAS MARKETS

    Choosing the Best Countries to Boost Your Export

    1. TOP OVERSEAS MARKETS FOR EXPORTING YOUR PRODUCT
    2. TOP CONSUMING MARKETS
    3. UNSATURATED MARKETS
    4. TOP IMPORTING MARKETS
    5. MOST PROFITABLE MARKETS

  7. 7. PRODUCTION

    The Latest Trends and Insights into The Industry

    1. PRODUCTION VOLUME AND VALUE: HISTORICAL DATA (2012–2024) AND FORECAST (2025–2035)
    2. PRODUCTION BY COUNTRY: HISTORICAL DATA (2012–2024) AND FORECAST (2025–2035)

  8. 8. IMPORTS

    The Largest Import Supplying Countries

    1. IMPORTS: HISTORICAL DATA (2012–2024) AND FORECAST (2025–2035)
    2. IMPORTS BY COUNTRY: HISTORICAL DATA (2012–2024) AND FORECAST (2025–2035)
    3. IMPORT PRICES BY COUNTRY: HISTORICAL DATA (2012–2024) AND FORECAST (2025–2035)

  9. 9. EXPORTS

    The Largest Destinations for Exports

    1. EXPORTS: HISTORICAL DATA (2012–2024) AND FORECAST (2025–2035)
    2. EXPORTS BY COUNTRY: HISTORICAL DATA (2012–2024) AND FORECAST (2025–2035)
    3. EXPORT PRICES BY COUNTRY: HISTORICAL DATA (2012–2024) AND FORECAST (2025–2035)

  10. 10. PROFILES OF MAJOR PRODUCERS

    The Largest Producers on The Market and Their Profiles

  11. 11. COUNTRY PROFILES

    The Largest Markets And Their Profiles

    This Chapter is Available Only for the Professional Edition PRO
    • United States
    • China
    • Japan
    • Germany
    • United Kingdom
    • France
    • Brazil
    • Italy
    • Russian Federation
    • India
    • Canada
    • Australia
    • Republic of Korea
    • Spain
    • Mexico
    • Indonesia
    • Netherlands
    • Turkey
    • Saudi Arabia
    • Switzerland
    • Sweden
    • Nigeria
    • Poland
    • Belgium
    • Argentina
    • Norway
    • Austria
    • Thailand
    • United Arab Emirates
    • Colombia
    • Denmark
    • South Africa
    • Malaysia
    • Israel
    • Singapore
    • Egypt
    • Philippines
    • Finland
    • Chile
    • Ireland
    • Pakistan
    • Greece
    • Portugal
    • Kazakhstan
    • Algeria
    • Czech Republic
    • Qatar
    • Peru
    • Romania
    • Vietnam

  12. LIST OF TABLES

    1. Key Findings In 2024
    2. Market Volume, In Physical Terms: Historical Data (2012–2024) and Forecast (2025–2035)
    3. Market Value: Historical Data (2012–2024) and Forecast (2025–2035)
    4. Per Capita Consumption, by Country, 2022–2024
    5. Production, In Physical Terms, By Country: Historical Data (2012–2024) and Forecast (2025–2035)
    6. Imports, In Physical Terms, By Country: Historical Data (2012–2024) and Forecast (2025–2035)
    7. Imports, In Value Terms, By Country: Historical Data (2012–2024) and Forecast (2025–2035)
    8. Import Prices, By Country: Historical Data (2012–2024) and Forecast (2025–2035)
    9. Exports, In Physical Terms, By Country: Historical Data (2012–2024) and Forecast (2025–2035)
    10. Exports, In Value Terms, By Country: Historical Data (2012–2024) and Forecast (2025–2035)
    11. Export Prices, By Country: Historical Data (2012–2024) and Forecast (2025–2035)

  13. LIST OF FIGURES

    1. Market Volume, In Physical Terms: Historical Data (2012–2024) and Forecast (2025–2035)
    2. Market Value: Historical Data (2012–2024) and Forecast (2025–2035)
    3. Consumption, by Country, 2024
    4. Market Volume Forecast to 2035
    5. Market Value Forecast to 2035
    6. Market Size and Growth, By Product
    7. Average Per Capita Consumption, By Product
    8. Exports and Growth, By Product
    9. Export Prices and Growth, By Product
    10. Production Volume and Growth
    11. Exports and Growth
    12. Export Prices and Growth
    13. Market Size and Growth
    14. Per Capita Consumption
    15. Imports and Growth
    16. Import Prices
    17. Production, In Physical Terms: Historical Data (2012–2024) and Forecast (2025–2035)
    18. Production, In Value Terms: Historical Data (2012–2024) and Forecast (2025–2035)
    19. Production, by Country, 2024
    20. Production, In Physical Terms, by Country: Historical Data (2012–2024) and Forecast (2025–2035)
    21. Imports, In Physical Terms: Historical Data (2012–2024) and Forecast (2025–2035)
    22. Imports, In Value Terms: Historical Data (2012–2024) and Forecast (2025–2035)
    23. Imports, In Physical Terms, By Country, 2024
    24. Imports, In Physical Terms, By Country: Historical Data (2012–2024) and Forecast (2025–2035)
    25. Imports, In Value Terms, By Country: Historical Data (2012–2024) and Forecast (2025–2035)
    26. Import Prices, By Country: Historical Data (2012–2024) and Forecast (2025–2035)
    27. Exports, In Physical Terms: Historical Data (2012–2024) and Forecast (2025–2035)
    28. Exports, In Value Terms: Historical Data (2012–2024) and Forecast (2025–2035)
    29. Exports, In Physical Terms, By Country, 2024
    30. Exports, In Physical Terms, By Country: Historical Data (2012–2024) and Forecast (2025–2035)
    31. Exports, In Value Terms, By Country: Historical Data (2012–2024) and Forecast (2025–2035)
    32. Export Prices, By Country: Historical Data (2012–2024) and Forecast (2025–2035)

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